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作者报告了48例急性白血病患者的骨髓髓系白血病细胞集落(AML-CFU)和粒-单核细胞集落(GM-CFU)体外培养的结果。结果表明,急非淋白血病治疗前AML-CFU数比缓解组高,而GM-CFU比缓解组低,差异显著。观察14例急非淋白血病患者治疗前AML-CFU数与预后的关系,发现AML-CFU丛/集比值具有判断预后的价值,AML-CFU数与此无关。本文还提出,AML-CFU培养用于微小残余白血病的诊断必须结合形态观察。
The authors report the results of in vitro culture of bone marrow myeloid leukemia cell colonies (AML-CFU) and granulocyte-mononuclear cell colonies (GM-CFU) in 48 patients with acute leukemia. The results showed that acute leukemias before treatment AML-CFU number higher than the remission group, and GM-CFU lower than the remission group, the difference was significant. The relationship between the number of AML-CFU and the prognosis of 14 cases of acute non-leukemia patients before treatment was observed. It was found that the ratio of AML-CFU cluster / set has the value of prognosis, and the number of AML-CFU has nothing to do with this. This article also proposed that AML-CFU culture for the diagnosis of minimal residual leukemia must be combined with morphological observation.