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对204例糖尿病患者组成的研究组和由259例健康者组成的对照组进行A型行为类型(TABP)评定量表和特质应对方式问卷(TCSQ)的调查以及血浆皮质醇(F)和糖化血红蛋白(Hb A1c)水平的测定,并根据问卷评定结果将研究组分为A型积极应对亚组(A型者中积极应对分数高于平均分)和A型消极应对亚组(A型行为者中消极应对分数高于平均分),同时对各亚组进行血浆皮质醇(F)、糖化血红蛋白和应对方式分数的相关性分析。结果研究组中A型消极应对亚组的血浆皮质醇水平和糖化血红蛋白水平均高于A型积极应对亚组;消极应对分数与血浆皮质醇水平呈正相关,血浆皮质醇水平和糖化血红蛋呈正相关,差异均有统计学意义。研究组A型积极应对亚组的积极应对分数与血浆皮质醇水平,以及血浆皮质醇水平与糖化血红蛋白水平均无相关性。结论 A型行为伴消极应对方式对糖尿病患者有一定影响作用。关注个体的不良心理应激特征对预防糖尿病有重要意义。
A total of 204 diabetes mellitus patients and 259 healthy volunteers were enrolled in the TABP Rating Scale and the Trait Counterstroke Questionnaire (TCSQ), and plasma cortisol (F) and HbA1c (Hb A1c) were measured and the study group was divided into A positive response subgroup (positive response score above average) and A negative response subgroup (type A) Negative coping scores were higher than the average score). Meanwhile, the correlation analysis of plasma cortisol (F), HbA1c and coping style scores in each subgroup was analyzed. Results The level of plasma cortisol and glycated hemoglobin in subgroup A of the study group were both higher than those in subgroup A; negative response score was positively correlated with plasma cortisol level, and plasma cortisol level was positively correlated with glycated hemoglobin , The differences were statistically significant. There was no correlation between the active coping scores and plasma cortisol level, as well as plasma cortisol level and HbA1c in the study group. Conclusion A type of behavior with negative coping style has a certain effect on patients with diabetes. Concerned about the individual characteristics of adverse psychological stress prevention of diabetes is of great significance.