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目的 :评价胃肠起搏器治疗胃动力紊乱性疾病的有效性和安全性。方法 :胃肠起搏器治疗 30例胃动力紊乱性疾病患者 (治疗组 ) ,并与胃肠起搏空白输出机治疗组及普瑞博思治疗组对照比较。治疗前后检查胃电图 ,记录胃电频率、幅值 ,观察临床症状。结果 :治疗组、空白组、普瑞博思组的临床症状总有效率分别为 90 .0 %、4 6 .6 %、86 .7% ,治疗组和普瑞博思组的治疗前后症状积分比较差别有显著性 (P<0 .0 5 ) ;治疗组治疗后胃电图空腹、餐后平均频率较治疗前明显改善 (P<0 .0 5 ) ,趋向正常频率 ;普瑞博思组仅治疗后餐后胃电平均频率较治疗前有改善(P<0 .0 5 ) ,空白组胃电频率治疗前后差异无统计学意义。结论 :胃肠起搏器治疗胃动力紊乱性疾病可改善临床症状及胃电生理的频率。
Objective: To evaluate the effectiveness and safety of gastrointestinal pacemaker in the treatment of gastric motility disorder. Methods: Gastrointestinal pacemaker was used to treat 30 patients with gastric motility disorders (treatment group), and compared with control group of gastrointestinal pacing blank output machine and Puri Bose treatment group. Before and after treatment, check the EGG, record the frequency of gastric electrical, amplitude, observe the clinical symptoms. Results: The total effective rate of clinical symptoms in treatment group, blank group and prebris group were 90.0%, 46.6% and 86.7% respectively. The difference of symptom scores between the treatment group and the pregabs group before and after treatment was significant (P <0.05). After treatment, the electrogastrogram fasting and postprandial average frequency in the treatment group were significantly improved (P <0.05), and tended to the normal frequency. After treatment with the pregabal group only The average postprandial gastric electrical frequency was improved compared with those before treatment (P <0.05), and there was no significant difference in the frequency of gastric electrical activity between before and after treatment in the blank group. Conclusion: Gastrointestinal pacemaker treatment of gastric motility disorders can improve the clinical symptoms and gastric electrophysiology frequency.