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毛细胞白血病(hairy cell leukemia,HCL)的特征是全血细胞减少,外周血有明显细胞浆突出的单核细胞,有中度至重度脾大而无明显淋巴腺病。对本病常用的治疗方法之一是脾切除术,据报道对许多病例有效。作者研究了一组施脾切除的HCL患者,旨在寻找脾切除术疗效的预后标志。 65例施脾切除的HCL患者,男54、女11例,年龄30~80岁。患者脾切除前1周内和切脾后2~12周的血细胞计数和脾重量资料齐全,切脾后随访1~3
Hairy cell leukemia (HCL) is characterized by pancytopenia, peripheral blood cells were significantly prominent mononuclear cells, with moderate to severe splenomegaly without obvious lymphatic disease. One of the commonly used treatments for this disease is splenectomy, which is reported to be effective in many cases. The authors studied a group of patients with splenectomy for the purpose of finding prognostic markers of splenectomy. 65 cases of splenectomy HCL patients, 54 males and 11 females, aged 30 to 80 years. Patients within 1 week before splenectomy and 2 to 12 weeks after splenectomy blood cell count and spleen weight data are complete, followed by splenectomy 1 ~ 3