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目的分析腹腔镜下胃癌手术治疗效果,为临床医学提供依据。方法 32例胃癌患者,依照手术方法分为腹腔镜组15例(腹腔镜下手术)和开腹组17例(常规开腹胃癌手术),对比分析两组患者治疗前后凝血酶原时间(PT)、纤维蛋白原(FIB)以及活化部分凝血活酶时间(APTT)。结果手术前后患者的APTT和国际标准化比值(INR)变化差异无统计学意义(P>0.05),PT明显减小(P<0.05),两组患者凝血指标变化比较差异无统计学意义(P>0.05)。手术前后比较患者的FIB和血浆中D-二聚体(D-D)均明显升高(P<0.05);术后24 h,腹腔镜组患者的FIB、D-D明显高于开腹组(P<0.05)。结论采用腹腔镜手术治疗胃癌患者同样会使患者呈现高凝状态,需要在围手术期做好预防措施。
Objective To analyze the effect of laparoscopic surgery for gastric cancer and provide the basis for clinical medicine. Methods Thirty-two patients with gastric cancer were divided into laparoscopic group (laparoscopic surgery) and open group (laparoscopic surgery) according to the method of surgery. Prothrombin time (PT) was compared between the two groups before and after treatment. , Fibrinogen (FIB), and activated partial thromboplastin time (APTT). Results There was no significant difference in APTT and INR between before and after operation (P> 0.05) and PT (P <0.05). There was no significant difference in coagulation index between the two groups (P> 0.05). FIB and DD in plasma and plasma were significantly higher in patients before and after surgery (P <0.05), and those in laparoscopic group were significantly higher than those in open group at 24 h ). Conclusion Laparoscopic surgery for patients with gastric cancer will also make patients with hypercoagulable state, the need for preventive measures in the perioperative period.