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本文报告1例不寻常病例。此例其母亲为慢性HBV感染者(HB_SAg阳性,抗HBe阳性)的7岁越南女孩在常规检查时发现其血清HB_SAg和HBeAg均阳性,其3位同胞中2位抗HB_S阳性,另一位所有HBV指标均阴性。进一步检查发现其AST轻度升高,HBV-DNA阳性,IgM抗HBc和HDV的全抗体均阴性。肝活检提示慢性迁延性肝炎。对肝切片作免疫组织化学染色的结果提示,约10％的肝细胞胞质有HB_SAg、前-S_1、细胞核有HBcAg和
This article reports an unusual case. In this case, a 7-year-old Vietnamese girl whose mother was a chronic HBV infection (positive for HB_SAg and positive for anti-HBe) was found to have positive serum HB_SAg and HBeAg in routine examination, 2 of the 3 sibs were positive to HB_SSA, and the other HBV indicators were negative. Further examination revealed a mild increase in AST, HBV-DNA positive, IgM anti-HBc and HDV antibodies were negative. Liver biopsy suggests chronic persistent hepatitis. The results of immunohistochemical staining of liver sections suggested that about 10% of liver cells had HB_SAg in the cytoplasm, pre-S_1 and HBcAg in the nucleus