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目的分析卡维地洛联合依那普利用于治疗老年风湿性心脏病对患者心力衰竭症状的影响。方法 92例老年风湿性心脏病心力衰竭患者作为研究对象,随机将患者分为观察组和对照组,各46例。其中对照组单纯给予依那普利治疗,观察组利用卡维地洛联合依那普利进行治疗。比较两组疗效及治疗前后心功能指标情况。结果观察组患者治疗总有效率(93.5%)显著高于对照组(73.9%)(P<0.05)。观察组治疗后的心率(HR)、收缩压(SBP)和舒张压(DBP)均优于对照组,心力衰竭评分高于对照组(P<0.05)。观察组患者心室重构各项指标改善情况均优于对照组(P<0.05)。结论卡维地洛联合依那普利用于治疗老年风湿性心脏病对患者心力衰竭症状改善疗效确切,可在临床推广。
Objective To analyze the effect of carvedilol and enalapril on the treatment of senile rheumatic heart disease in patients with heart failure symptoms. Methods A total of 92 elderly patients with rheumatic heart disease and heart failure were randomly divided into observation group and control group, with 46 cases in each group. The control group was given enalapril and the observation group was treated with carvedilol and enalapril. The curative effect and the cardiac function before and after treatment were compared between the two groups. Results The total effective rate (93.5%) in observation group was significantly higher than that in control group (73.9%) (P <0.05). Heart rate (HR), systolic blood pressure (SBP) and diastolic blood pressure (DBP) in the observation group were better than those in the control group, and heart failure scores were higher than those in the control group (P <0.05). The improvement of ventricular remodeling in observation group was better than that in control group (P <0.05). Conclusion The combination of carvedilol and enalapril for the treatment of elderly patients with rheumatic heart failure to improve the symptoms of heart failure exact effect can be clinically promoted.