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[目的]探讨年龄≤35岁年轻宫颈癌发病相关因素、临床病理特点等。[方法]回顾分析1999￣2007年年龄≤35岁年轻宫颈癌患者58例,并与>35岁中老年组269例临床资料进行对比分析。[结果]年轻宫颈癌组中临床分期原位癌占17.24%,Ⅰ期占53.45%,两者共占70.69%。年轻组中临床表现主要为接触性阴道出血(63.79%,37/58)。发现脉管内癌栓者占34.78%(16/46),发现盆腔淋巴结转移者占32.61%(15/46),与中老年宫颈癌组比较均有显著性差异(P<0.05)。年轻组和中老年组在组织病理学类型、组织学分级、宫颈形态、癌灶大小及宫颈肌层浸润深度方面无差异。[结论]年轻宫颈癌临床分期以早期癌为主,盆腔淋巴结转移率和脉管浸润程度高于中老年宫颈癌组。应重视宫颈癌疾病预防知识的教育及年轻女性的宫颈筛查。
[Objective] To investigate the incidence of cervical cancer younger than 35 years of age related factors, clinical and pathological features. [Methods] A retrospective analysis of 58 cases of young cervical cancer aged ≤ 35 years old from 1999 to 2007 was conducted, and compared with 269 cases of clinical data of middle-aged and elderly patients aged 35 years. [Results] The clinical staging of carcinoma in situ in young cervical cancer group accounted for 17.24%, stage Ⅰ accounted for 53.45%, both accounted for 70.69%. The clinical manifestations of young group mainly contact vaginal bleeding (63.79%, 37/58). Found that intravascular thrombolysis accounted for 34.78% (16/46), found pelvic lymph node metastasis accounted for 32.61% (15/46), and the elderly cervical cancer group were significantly different (P <0.05). There was no difference in the histopathological type, histological grade, cervical morphology, tumor size and depth of cervical myometrial invasion between young group and middle-aged group. [Conclusion] The clinical stage of young cervical cancer is mainly early stage, and the rate of pelvic lymph node metastasis and vascular infiltration is higher than that of middle-aged and elderly patients with cervical cancer. Should pay attention to cervical cancer prevention knowledge education and cervical screening of young women.