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目的探讨凝血与纤溶指标的动态变化在产科DIC诊断中的意义。方法正常产妇产前状态;发生DIC产妇的产前状态,生产过程中DIC状态的标本各50例进行凝血和纤溶指标的检测。50例正常非孕妇女作对照。结果与非孕妇比,正常产妇的各种凝血相关时间缩短,Fib升高;而发生DIC的产妇在产前状态时,各种凝血时间延长,Fib降低,D-二聚体升高,并随着DIC的发展而发生进行性变化。结论产科DIC的各种凝血与纤溶指标在产前就已发生明显变化,动态监测凝血状态对DIC作出早期诊断有重要价值。
Objective To investigate the significance of dynamic changes of coagulation and fibrinolysis in the diagnosis of obstetric DIC. Methods Prenatal status of normal maternal; Prenatal status of DIC maternal, DIC status in the production process of 50 cases of coagulation and fibrinolysis were detected. 50 cases of normal non-pregnant women as a control. Results Compared with non-pregnant women, normal maternal coagulation-related time shortened, Fib increased; while the occurrence of DIC in prenatal conditions, the various clotting time, Fib decreased, D-dimer increased, and with With the development of DIC and the progressive changes have taken place. Conclusions Various indexes of coagulation and fibrinolysis in obstetric DIC have changed obviously in prenatal period. Dynamic monitoring of coagulation state is of great value in the early diagnosis of DIC.