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目的了解马法兰隔离肝灌注治疗不可切除晚期肝癌的疗效。方法2003年3月,在治疗不可切除性原发性肝癌中采用了高温下马法兰隔离肝灌注治疗。结果术后第6天,肿瘤组织出现了明显的液化、坏死。结论马法兰隔离肝灌注治疗是治疗不可切除性原发性肝癌的新技术。熟练的外科医生,不仅要了解马法兰隔离肝灌注治疗手术前的并发症,更要在术前术后对病人进行仔细监测,以避免急性凝血功能损害以及肝肾功能衰竭。
Objective To investigate the curative effect of melphalan isolated hepatic perfusion in the treatment of unresectable advanced liver cancer. Methods March 2003, in the treatment of unresectable primary liver cancer using melphalan isolated hepatic perfusion therapy. Results On the 6th day after operation, the tumor tissues showed obvious liquefaction and necrosis. Conclusion Mafalan isolated hepatic perfusion therapy is a new technique for the treatment of unresectable primary liver cancer. Skilled surgeons should not only understand the preoperative complications of melphalan, but also carefully monitor the patient before and after surgery to avoid acute coagulation damage and liver and kidney failure.