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山莨菪碱(anisodamine,Ani)具有外周抗M胆碱受体作用,在临床上的应用十分广泛,常用于抢救感染中毒性休克、眩晕病及血管疾患等,有调节微循环、扩张小血管、缓解平滑肌痉挛及镇痛等作用,应用其中一种作用时,其他的作用则成为副作用。临床上青光眼和前列腺肥大患者禁用山莨菪碱,出现阿托品样中毒症状时可用拟胆碱药毛果芸香碱解救,皮下注射5~10 mg,间隔15 min 1次,直到症状减轻。
Anisodamine has the function of peripheral anti-M choline receptor, and is widely used clinically in the rescue of toxic shock, vertigo and vascular diseases. It has the functions of regulating microcirculation, dilating small blood vessels, Relieve smooth muscle spasm and analgesic effect, the application of one of the role, the other role has become a side effect. Clinically, patients with glaucoma and prostatic hyperplasia banned anisodamine, atropine-like poisoning symptoms can be treated with pilocarpine quinetic cholinergic, subcutaneous injection of 5 ~ 10 mg, 15 min intervals 1, until the symptoms reduced.