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人体大部分感染起始于粘膜，因此阻断粘膜表面感染具有重要意义。粘膜表面的保护作用主要来源于分泌性免疫球蛋白。本文综述了参与粘膜表面免疫力的各种免疫球蛋白的来源、作用机理及其影响因素。这将有利于对抵御病原体入侵的防御机理的认识，并为发展粘膜免疫提供新策略。
Most human infections start in the mucosa, so blocking mucosal surface infection is of great significance. The protective effect of mucosal surface mainly comes from secreted immunoglobulin. This review summarizes the origin, mechanism and influencing factors of various immunoglobulins involved in mucosal surface immunity. This will help to understand the mechanism of defense against the invasion of pathogens and provide a new strategy for the development of mucosal immunity.