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目的观察疏血通注射液治疗短暂性脑缺血(TIA)发作的疗效及血液流变学的变化。方法回顾天津市职业病防治院2011年2月-2013年12月收治的98例缺血性脑血管病患者,随机分成观察组与对照组,两组均在控制患者血糖等基础病变的同时,给予静脉滴注治疗。其中,观察组50例患者给予疏血通注射液静脉滴注;对照组48例患者给予舒血宁注射液加入0.9%Nacl250ml注射液中静脉滴注,两组疗程均为14d,并于治疗结束后又随访60d。结果观察组的治疗总有效率明显高于对照组。观察组在进行治疗后Fg下降明显,PT与APTT明显延长,与对照组存在明显差异。两组疗效比较,差异有统计学意义(P<0.05)。结论疏血通注射液治疗缺血性脑血管病具有降低纤维蛋白原、改善大脑循环、改善血黏度等作用,疗效显著。
Objective To observe the effect of Shuxuetong injection on the treatment of transient ischemic attack (TIA) and the change of hemorheology. Methods A retrospective study of 98 patients with ischemic cerebrovascular disease admitted to Tianjin Occupational Disease Prevention and Control Hospital from February 2011 to December 2013 were randomly divided into observation group and control group. Both groups were given control of basic diseases such as blood glucose, Intravenous infusion therapy. Among them, the observation group of 50 patients given Shuxuetong injection intravenous infusion; control group of 48 patients given Shuxuening injection by adding 0.9% Nacl250ml injection intravenous drip, the two courses were 14d, and at the end of treatment After a follow-up 60d. Results The total effective rate of observation group was significantly higher than that of control group. After treatment, the observation group Fg decreased significantly, PT and APTT significantly prolonged, there was a significant difference with the control group. The curative effect between the two groups, the difference was statistically significant (P <0.05). Conclusion Shuxuetong injection for the treatment of ischemic cerebrovascular disease with lower fibrinogen, improve cerebral circulation, improve blood viscosity and other effects, the effect is significant.