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系统性红斑狼疮(SLE)是一种结缔组织疾病,累及多个系统,临床表现复杂多样;近年国内外对该病的研究日渐重视,文献报导亦渐多,使该病的诊断、治疗及免疫学研究有了很大进展。现将15年来广州市第一人民医院与广州医学院附属医院住院SLE125例,作一报导,并结合文献,着重对该病的诊断和治疗问题进行讨论。临床资料分析一、诊断标准全部病例皆符合下列标准之一:(1) 有多脏器损害,且SLE细胞检查阳性者;(2) 有皮肤病变,又合并内脏损害,皮肤活检阳性者;(3) 典型SLE的多系统损害,病程中抗核抗体滴度升高者。
Systemic lupus erythematosus (SLE) is a connective tissue disease involving multiple systems, the clinical manifestations of complex and diverse; in recent years, more and more attention to the study of the disease at home and abroad, literature reports are also increasing, the disease diagnosis, treatment and immune Research has made great progress. Now 15 years Guangzhou First People’s Hospital and Guangzhou Medical College Affiliated Hospital SLE125 cases, made a report, combined with the literature, focusing on the diagnosis and treatment of the disease are discussed. Clinical data analysis First, the diagnostic criteria All cases are in line with one of the following criteria: (1) multiple organ damage, and SLE cells were positive; (2) skin lesions, combined with visceral damage, skin biopsy positive; ( 3) typical SLE multi-system damage, anti-nuclear antibody titers in the course of the disease.