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甲状旁腺癌是一种罕见的恶性肿瘤。病人常出现典型的骨、肾病变,可有血钙和甲状旁腺激素的明显升高,70%的病人可扪及甲状旁腺肿瘤。影像学检查多可明确定位,但难以鉴别性质。冰冻病理对甲状旁腺癌诊断价值有限,而标本大体外观却非常特异。肿瘤易复发,首次手术中整块地根治性切除肿瘤病灶是降低复发率、改善预后的关键因素。一旦复发,应努力明确转移部位和扩散范围,争取再次切除病灶,药物控制高钙血症,改善病人生存质量,延长生存期。
Parathyroid cancer is a rare malignancy. Patients often appear typical bone and kidney disease, there may be a significant increase in serum calcium and parathyroid hormone, 70% of patients palpable parathyroid tumor. Imaging examination can be more clear positioning, but difficult to identify the nature. Frozen pathological diagnosis of parathyroid cancer is of limited value, but the general appearance of the specimen is very specific. Tumor recurrence, the first operation of the block radical resection of tumor lesions is to reduce the recurrence rate and improve the prognosis of the key factors. Once the recurrence, efforts should be made to clear the transfer site and extent of dissemination, and strive to remove the lesion again, drug control of hypercalcaemia, improve patient quality of life and prolong survival.