论文部分内容阅读
为了评价肌凝蛋白重链的释放与心肌坏死面积之间的相关性。连续测定55例急性心梗患者血清肌凝蛋白重链片段的浓度。应用溶栓制剂成功地治疗了8倒患者,其余患者未接受该治疗。采用相同的肌凝蛋白测定法,对25条实验性心梗狗的血清进行了研究,其中6条狗成功地接受溶栓治疗。对不伴有并发症心梗患者,肌凝蛋白浓度的时相过程呈典型的单相曲线。将肌凝蛋白释放的动力学数值与其他结果相比较,对不同组患者的测定的结果表明:累计的肌凝蛋白释放数,与累计的肌酸激酶(CK),CK-MB,乳酸脱氢酶释放致以及铊~(201)的分布均有显著的相关性。
To assess the correlation between myosin heavy chain release and myocardial necrosis area. Serum concentration of myosin heavy chain fragment was determined continuously in 55 patients with acute myocardial infarction. Eight patients were successfully treated with thrombolytic agents, and the remaining patients did not receive the treatment. Using the same myosin assay, sera from 25 experimental myocardial infarction dogs were studied, of which 6 dogs were successfully treated with thrombolytic therapy. The phase process of myosin concentration in patients without myocardial infarction was a typical single-phase curve. The kinetic values of myosin release were compared with those of other results and the results for the different groups of patients showed that the cumulative number of myosin released was correlated with accumulated creatine kinase (CK), CK-MB, lactate dehydrogenation The release of enzyme and the distribution of thallium ~ (201) were significantly correlated.