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本文测定了16名长期停服棉酚男子血清FSH、LH和睾丸酮(T)的水平。停服棉酚后,精子计数为零的7名受试者,血清FSH和LH水平显著高于正常对照组;血清T略低于正常对照组,而T/LH值则显著低于正常对照组。表明睾丸功能受到不同程度的损伤。另外9名停服棉酚后,精子计数完全恢复者,除血FSH高于对照组外,其余指标与正常对照组比较均无显著性差异。提示当棉酚剂量尚未使生精过程受到不可逆性损伤时,其间质细胞的功能受损可能不大。
This article measured 16 long-term gossypol male serum FSH, LH and testosterone (T) levels. Serum FSH and LH levels were significantly higher in 7 subjects with no sperm count after stopping gossypol than in normal control group; serum T was slightly lower than that of normal control group, while T / LH value was significantly lower than that of normal control group . Testicular function showed varying degrees of damage. The other nine stop gossypol sperm count was fully recovered, except for the blood FSH higher than the control group, the remaining indicators compared with the normal control group no significant difference. Tip gossypol dose has not yet caused the process of spermatogenesis irreversible damage, the functional impairment of interstitial cells may not be large.