论文部分内容阅读
目的对艾普拉唑肠溶片的不良反应报告进行统计分析,评估其安全性及相关影响因素。方法对2008年6月~2016年6月期间,通过广东省和国家药品不良反应监测系统网络上报的77例艾普拉唑肠溶片的不良反应报告进行统计分析。结果艾普拉唑肠溶片的不良反应以胃肠道反应、皮疹和头晕头痛为主;严重不良反应少见。结论临床使用艾普拉唑相对比较安全,但应用时需按说明书剂量使用并关注合并用药情况,同时加强用药后复诊和随访,减少不良反应的发生。
Objective To analyze the adverse reactions of ioprazole enteric-coated tablets and evaluate its safety and related factors. Methods From June 2008 to June 2016, 77 cases of ilaprazole enteric-coated adverse reactions reported by Guangdong Province and the national network of adverse drug reaction monitoring system were statistically analyzed. Results The adverse reactions of ilaprazole enteric-coated tablets were mainly gastrointestinal reactions, skin rashes and dizziness and headache. Severe adverse reactions were rare. Conclusions The clinical use of ilaprazole is relatively safe, but the dosage should be used according to the instruction manual and pay attention to the combination medication, and strengthen the referral and follow-up after medication to reduce the occurrence of adverse reactions.