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三兄弟共患食管癌钱立庭程广源赵于飞食管癌高发区存在明显的家族聚集性。遗传学分析提示:在某高发区人群中约有19%的居民拥有一隐性遗传易感基因,作者报道2个家族中各有3兄弟均患食管癌的病例,提示食管癌发病的遗传背景。临床资料见附表。其中甲组三兄弟的父亲死...
Three brothers co-existing esophageal cancer Qian Liting Cheng Guangyuan Zhao Yufei Esophageal cancer high-incidence areas there is a clear family aggregation. Genetic analysis suggests that about 19% of residents in a high-risk population have a recessive genetic susceptibility gene. The authors report that 3 brothers in each of the 2 families have esophageal cancer, suggesting the genetic background of esophageal cancer. . See clinical data in the attached table. Among them, the father of the three brothers of the first group died...