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目的观察长期家庭氧疗(LTDOT)对慢性阻塞性肺病(COPD)患者PaO2、PaCO2、肺功能、COPD急性发作率的影响。方法将在我院门诊长期随访的40例COPD患者随机分为两组,常规治疗相同,治疗组于缓解期后进行长期家庭氧疗,对照组于缓解期后无氧疗。两组患者于治疗前及治疗后第6月、第12月测定肺功能、动脉血气分析等指标,并统计COPD急性发作的比率。结果 COPD患者长期家庭氧疗后PaO2明显升高,FEV1有缓慢升高;对照组PaO2进行性下降,FEV1进行性下降,COPD急性发作率高于治疗组。结论 COPD患者长期家庭氧疗可提高PaO2,改善肺功能、改善生活质量、降低COPD急性发作的几率。
Objective To observe the effect of long-term home oxygen therapy (LTDOT) on the incidence of PaO2, PaCO2, pulmonary function and acute exacerbation of COPD in patients with chronic obstructive pulmonary disease (COPD). Methods Forty COPD patients who were followed up for a long time in our hospital were randomly divided into two groups. The routine treatment was the same. The treatment group received long-term home oxygen therapy after remission and the control group received no oxygen therapy after remission. Two groups of patients before and after treatment in the first 6 months, December measured lung function, arterial blood gas analysis and other indicators, and statistical COPD acute attack rate. Results After long-term home oxygen therapy, PaO2 was significantly increased and FEV1 was slowly increased in COPD patients. PaO2 was decreased and FEV1 was decreased in COPD patients. The acute episode rate of COPD was higher than that of the treatment group. Conclusion Long-term home oxygen therapy in patients with COPD can improve PaO2, improve lung function, improve quality of life and reduce the risk of acute exacerbation of COPD.