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目的探讨尿激酶与低分子肝素联合应用溶栓治疗急性缺血性脑梗死的临床治疗,提出治疗观察要点。方法将40例脑梗死应用尿激酶与低分子肝素溶栓治疗。观察40例患者溶栓前和溶栓后7 d按美国国立卫生院卒中评分(NIHSS),观察神经功能改善情况。结果 40例患者溶栓前评分(7.35±5.08)分,溶栓后评分(2.825±3.80)分,溶栓前后比较差异有统计学意义。结论中等剂量尿激酶与低分子肝素联合应用是治疗急性缺血性脑梗死的有效方法之一。溶栓后病情监测、并发症预防处理、有效的健康教育对促进患者恢复有重要作用。
Objective To investigate the clinical application of urokinase and low molecular weight heparin combined with thrombolytic therapy in the treatment of acute ischemic cerebral infarction. Methods Thirty patients with cerebral infarction were treated with urokinase and low molecular weight heparin. 40 patients were observed before and after thrombolysis thrombolysis 7 d according to the National Institutes of Health Stroke Scale (NIHSS) to observe the improvement of neurological function. Results The score of 40 patients before thrombolysis (7.35 ± 5.08) and after thrombolysis (2.825 ± 3.80) scores were statistically significant difference before and after thrombolysis. Conclusion The combination of medium dose urokinase with low molecular weight heparin is an effective method for the treatment of acute ischemic cerebral infarction. Thrombolysis after disease monitoring, prevention and treatment of complications, effective health education to promote the recovery of patients has an important role.