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应用ＡＢＣ免疫组织化学方法，结合图像定量分析，研究了１８只哮喘豚鼠结状神经节和Ｃ７～Ｔ５段脊神经节内神经激肽Ａ（ＮＫＡ）的变化。结果表明，哮喘时结状神经节及Ｃ７～Ｔ，段脊神经节内ＮＫＡ阳性细胞教分别增加了约３０．６％和３５．１％；ＮＫＡ平均密度分别增加了３５．２％和３１．７％，ＮＫＡ灰度值的改变也有极显著性意义（Ｐ＜０．０１）。结果提示一级传入系统的ＮＫＡ可能参与了哮喘发作的病理生理过程，是其发作的重要因素之一
ABC immunohistochemistry and quantitative image analysis were used to study the changes of neurokinin A (NKA) in the nodose ganglia and C7 ~ T5 spinal ganglia of 18 asthmatic guinea pigs. The results showed that the number of NKA positive cells in the nodose ganglia, C7-T and segment ganglion in asthma increased by about 30.6% and 35.1%, respectively; the average density of NKA increased by 35.2% and 31.7% respectively %, NKA grayscale changes also have significant significance (P <0.01). The results suggest that NKA, a primary afferent system, may be involved in the pathophysiological process of asthma attack, which is one of the important factors of its attack