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目的:分析头孢菌类抗生素药品不良反应产生的原因,为临床用药安全提供参考。方法:收集我院自2014年2月-2015年2月间共查处的头孢菌类抗生素致不良反应的报告50例,统计涉及的药品名称并分析累及人体各系统情况。结果:头孢哌酮引发的不良反应例数最多,11例(22.00%),其后依次为头孢替安9例(18.0%)、头孢噻吩8例(16.0%);累及的系统包括皮肤及其附件系统(52.00%)、消化系统(22.00%)、呼吸系统(12.00%)等。结论:在使用头孢菌类抗生素时应该加强服药后的检测,避免和降低不良反应发生情况。
Objective: To analyze the causes of adverse reactions of cephalosporin antibiotics and provide references for the safety of clinical medication. Methods: Fifty cases of adverse reactions caused by cephalosporin antibiotics were collected from February 2014 to February 2015 in our hospital. The names of the involved drugs were collected and analyzed to analyze the systemic conditions of the human body. Results: Cefoperazone caused the largest number of adverse reactions in 11 cases (22.00%), followed by cefotiam in 9 cases (18.0%) and cefalothipine in 8 cases (16.0%). The affected systems included the skin and its Annex system (52.00%), digestive system (22.00%), respiratory system (12.00%) and so on. Conclusion: In the use of cephalosporin antibiotics should be tested after taking medication to avoid and reduce the incidence of adverse reactions.