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前列腺素全合成的研究近十几年来曾引起了有机化学界和医药工业部门的极大重视。已经报道了大量的合成路线,其中Corey合成法(J Am Chem Soc 1969,91:5675)
The research on prostaglandin total synthesis has aroused the great attention of organic chemistry and pharmaceutical industry departments in recent ten years. A number of synthetic routes have been reported, with the Corey synthesis method (J Am Chem Soc 1969, 91: 5675)