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目的探究地塞米松对未足月胎膜早破孕妇妊娠结局的影响。方法 70例未足月胎膜早破孕妇,随机分为对照组和观察组,每组35例。对照组孕妇未使用地塞米松,观察组孕妇实施地塞米松治疗。比较两组孕妇妊娠结局、新生儿预后情况、破膜至分娩时间及产程。结果观察组孕妇脐带脱垂、产后出血、剖宫产、死产及新生儿死亡发生率均低于对照组,差异具有统计学意义(P<0.05)。治疗后,观察组新生儿Apgar评分为(8.06±3.44)分,对照组新生儿Apgar评分为(5.16±3.57)分,观察组新生儿Apgar评分高于对照组,差异具有统计学意义(t=3.461,P<0.05)。观察组孕妇破膜至分娩时间及产程均短于对照组,差异具有统计学意义(P<0.05)。结论地塞米松治疗未足月胎膜早破孕妇能有效缩短破膜至分娩时间及产程,提高产妇生产的安全性及新生儿的存活率,并能有效减少新生儿不良情况的发生,在临床应用中具有较高的推广价值。
Objective To investigate the effect of dexamethasone on pregnancy outcome in preterm premature rupture of membranes. Methods 70 cases of premature rupture of membranes of pregnant women were randomly divided into control group and observation group, 35 cases in each group. Control group pregnant women did not use dexamethasone, observation group pregnant women to implement dexamethasone treatment. Pregnancy outcomes, neonatal prognosis, rupture of membranes to delivery time and labor course were compared between the two groups. Results The incidences of umbilical cord prolapse, postpartum hemorrhage, cesarean section, stillbirth and neonatal death in observation group were lower than those in control group, with statistical significance (P <0.05). After treatment, Apgar score was (8.06 ± 3.44) in neonates in observation group and (5.16 ± 3.57) in neonates in control group, Apgar score in neonates was higher in observation group than in control group, the difference was statistically significant (t = 3.461, P <0.05). The observation group of rupture of membranes to delivery time and labor duration were shorter than the control group, the difference was statistically significant (P <0.05). Conclusion Dexamethasone treatment of preterm premature rupture of membranes in pregnant women can effectively shorten the time from rupture of membranes to labor and labor, improve the safety of maternal production and neonatal survival rate, and can effectively reduce the incidence of neonatal adverse reactions in the clinical Application has a higher promotional value.