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目的 研究分析子宫颈鳞癌中晚期同步放化疗的临床效果,并探讨影响远处转移的相关因素.方法 采用回顾性病例分析方法,选取经病理学证实的中晚期(Ⅱb～Ⅳa期)宫颈癌患者96例.通过查阅患者完整临床资料,统计放化疗近期效果;并采用门诊、电话随访方式,记录患者生存率和远处转移情况;单因素和多因素分析远处转移的影响因素.结果 近期疗效:有效率(RR)为71.9％(69/96),疾病控制率(DCR)为92.7％(89/96).盆腔淋巴结转移、治疗前Hb水平、治疗后SCC-Ag水平以及FIGO分期是影响宫颈鳞癌远处转移的影响因素(P＜0.05),而盆腔淋巴结转移、治疗后SCC-Ag水平以及FIGO分期是独立影响因素(P＜0.05).结论 对中晚期子宫颈鳞癌患者采用同步放化疗可获得良好效果,提高患者生存率.岔腔淋巴结转移、治疗后SCC-Ag水平以及FIGO分期是远处转移的独立影响因素.“,”Objective To investigate the clinical efficacy af synchronism chemoradiation on middle-late stage cervical squamous cell carcinomas and influencing factors of distant metastasis.Methods Totally 96 cases of pathologically con firmed middle-late stage cervical squamons cell carcinoma patients were selected,the recent efficacy of synchronism chemoradiation was recordedby consulting the complete clinical data.Outpatient and telephone follow-up were used to record the survival rate and distant metastasis,and the factors influencing distant metastasis were analyzed by univariate and multivariate analysis.Results The RR was 71.9％ (69/96),DCR was 92.7％ (89/96).Pelvic lymph node metastasis,the levels of Hb before treatment,the levels of SCC-Ag after treatment and FIGO clinical staging were the influencing factors on distant metastasis.Pelvic lymph node metastasis,the levels of SCC-Ag after treatment and FIGO clinical staging were independent influencing factors on distant metastasis.Conclusion Good clinical efficacy was obtained of middle-late stage cervical squamous cell carcinomas by treated with synchronism chemoradiation.Pelvic lymph node metastasis,the levels of SCC-Ag after treatment and FIGO clinical staging were independent influencing factors on distant metastasis.