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目的探讨大肠埃希菌肺炎患儿血清心肌酶变化的临床意义。方法选取54例大肠埃希菌肺炎患儿作为肺炎组,54例健康儿童作为健康对照组。入选儿童于入院第1天清晨抽取空腹外周静脉血2 mL,采用Olympus Au2700型全自动生化分析仪,测定肺炎组患儿及健康对照组儿童血清CK、CK-MB、α-羟丁酸脱氢酶(α-HBDH)、AST、LDH等心肌酶指标。结果肺炎组患儿血清CK、CK-MB、α-HBDH、AST及LDH[(158.1±36.4)U.L-1、(31.9±9.0)U.L-1、(159.9±35.2)U.L-1、(45.5±12.4)U.L-1、(299.5±41.1)U.L-1]较健康对照组[(109.6±27.9)U.L-1、(12.6±4.2)U.L-1、(115.3±16.0)U.L-1、(20.7±5.9)U.L-1、(143.7±34.4)U.L-1]均明显升高(Pa<0.05)。结论大肠埃希菌肺炎患儿的心肌酶明显升高,检测心肌酶有助于早期判断心肌损害,以便及时给予营养心肌的药物,保护心脏功能,控制疾病进展。
Objective To investigate the clinical significance of serum myocardial enzymes in children with Escherichia coli pneumonia. Methods 54 cases of children with Escherichia coli pneumonia were selected as pneumonia group and 54 healthy children as healthy control group. Children were selected on the first day of admission on the first day of fasting peripheral venous blood 2 mL, the use of Olympus Au2700 automatic biochemical analyzer in children with pneumonia and healthy children serum CK, CK-MB, α-hydroxybutyrate dehydrogenation Enzyme (α-HBDH), AST, LDH enzymes such as myocardial enzymes. Results Serum levels of CK, CK-MB, α-HBDH, AST and LDH [(158.1 ± 36.4) UL-1, (31.9 ± 9.0) UL-1, (159.9 ± 35.2) (12.6 ± 4.2) UL-1, (115.3 ± 16.0) UL-1, (20.7 ± 12.9) UL-1 and (299.5 ± 41.1) UL- 5.9) UL-1, (143.7 ± 34.4) UL-1] were significantly higher (Pa than 0.05). Conclusions Myocardial enzymes in children with Escherichia coli pneumonia are obviously increased. Detection of myocardial enzymes can help to judge myocardial damage in early time so as to timely give drugs to nourish myocardium, protect heart function and control disease progression.