Butein effects in colitis and interleukin-6/signal transducer and activator of transcription 3 expre

• 作 者: SeheDongLee JungWanChoe BeomJa
• 机 构: DivisionofGastroenterologyDepartmentofInternalMedicineKoreaUniversityMedicalCenterSeoul152-703SouthK
• 出 处: 世界胃肠病学杂志：英文版
• 发表日期: 2015年2期
• 关键词: BUTEIN Interleukin-6/signal TRANSDUCER and activat Butein Interleukin-6/signal t
• 基金项目: Supported by Grants from the National Research Foundation of Korea,No.R1102452； Korea University,No.K1220161； by experimental techniques from the Core Laboratory for Convergent Translational Research

AIM: To evaluate the effects of butein on inflammatory cytokines, matrix metalloproteinase-9(MMP-9), andcolitis in interleukin(IL)-10-/- mice.METHODS: To synchronize colitis, 8- to 10-wk-old IL-10-/- mice were fed pellet-chow containing piroxicam for 2 wk