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患者,男,66岁.因患慢性支气管炎、肺心病于1994年5月14日入院.经体检确诊为肺心病合并肺部感染.给予注射用头孢唑肟钠(益保世灵,原料:日本藤泽药品工业株式社,西南药业股份有限公司分装)1g加于0.9%氯化钠注射液250ml中,静滴,bid,用药10d后,患者自觉剧烈头痛、恶心、颈软、发热38.5℃持续5d.瞳孔等大.停药后头痛和发热即停.体检无其它阳性体症.因疗效显著,为巩固疗效停药后第4d又用同厂家、同批号、同剂量的头孢唑肟钠静滴,用药2d后又出现上述同样症状,特别是剧烈头痛,停药后又恢复正常.血尿常规及肝功无异常.痰培养有霉菌生长.
Patients, male, age 66. Due to chronic bronchitis, pulmonary heart disease was admitted to hospital on May 14, 1994. The diagnosis of pulmonary heart disease with pulmonary infection by physical examination given ceftizoxime sodium injection (Yi Bao Shiling, raw materials: Japan Fujisawa Pharmaceutical Co., Ltd., Southwest Pharmaceutical Co., Ltd. sub) 1g plus 0.9% sodium chloride injection 250ml, intravenous infusion, bid, medication 10d, the patient consciously severe headache, nausea, neck soft, fever 38.5 ℃ for 5d. Pupil and other large. After stopping the headache and fever stop. Physical examination without other positive symptoms due to significant effect, in order to consolidate the efficacy of drug withdrawal after 4d with the same manufacturer, with the same batch, the same dose of cefazolin Oxytocin sodium intravenous infusion, 2d after treatment with the same symptoms, especially in severe headache, withdrawal and returned to normal after hematuria and liver function without abnormal sputum culture with mold growth.