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博莱霉素(BLM)作为妇产科扁平上皮癌的辅助药物,其疗效不够肯定并容易引起不可逆性病变的肺纤维化等。作者对宫颈癌手术病例使用BLM的远期疗效进行了研究,结果是:1.BLM全身给药的病例中,静脉滴注12例,动脉持续注射7例,共计19例,其远期疗效为:T_36例中4例,N_25例中4例生存期2～4年;T_210例,N_18例5年的生存率为100%。2.BLM局部给药的病例中,用油剂BLM子宫阴道注射15例,宫颈内放入丸剂2例,使用阴道栓剂、软膏1例,共计18例。按TNM分类:T_29例,T_19例N_14例,N_014例,M_018例,全部病例无一例死亡。
Bleomycin (BLM) as a secondary drug for obesity in obstetrics and gynecology flat epithelial cancer, its efficacy is not sure and easily lead to irreversible lesions such as pulmonary fibrosis. The authors studied the long-term efficacy of using BLM in cervical cancer surgery. The results were as follows: 1. In the case of systemic administration of BLM, 12 cases were infused intravenously and 7 cases were injected with arterial continuous injection in a total of 19 cases. The long-term effect was : T_36 cases in 4 cases, N_25 cases, 4 cases of survival of 2 to 4 years; T_210 cases, N_18 5-year survival rate was 100%. 2. BLM local administration of the case, with oil BLM uterus intravaginal injection in 15 cases, 2 cases of cervical pelvic injection, the use of vaginal suppository, ointment in 1 case, a total of 18 cases. According to TNM classification: T_29 cases, T_19 cases N_14 cases, N_014 cases, M_018 cases, no case of death in all cases.