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目的分析孟鲁司特钠联合布地奈德治疗小儿咳嗽变异性哮喘的临床效果。方法选择2013年2年—2014年2月治疗咳嗽变异性哮喘的患儿58例,随机分成对照组和治疗者两组,每组29例。对照组患儿采用布地奈德治疗,治疗组患儿在对照组基础上加用孟鲁司特钠,观察两种患儿的治疗效果。结果经过治疗后,对照组患儿每月日间、夜间哮喘发作次数及每月使用短效支气管扩张剂天数明天多于治疗组患儿,差异显著(P<0.05);对照组患儿肺功能第1秒用力呼气容积、呼气峰流速明显小于治疗组患儿,差异显著(P<0.05);对照组患儿治疗总有效率为68.97%明显低于治疗者患儿93.10%的治疗总有效率,差异显著(P<0.05)。结论采用孟鲁司特钠联合布地奈德治疗小儿咳嗽变异性哮喘的效果明显,能有效的改善临床症状、肺功能,提高治疗效果,值得推广。
Objective To analyze the clinical effect of combination of montelukast and budesonide on children with cough variant asthma. Methods Fifty-eight children with cough variant asthma were selected from 2 years in 2013 to February 2014, and were randomly divided into control group and treatment group, with 29 cases in each group. The control group of children with budesonide treatment, treatment group children in the control group based on the use of montelukast sodium, two children were observed treatment. Results After treatment, the daily number of asthma attacks and monthly use of short-acting bronchodilators in the control group were significantly higher than those in the treatment group every day in the control group (P <0.05). The pulmonary function 1 second forced expiratory volume, expiratory peak velocity was significantly smaller than the treatment group children, the difference was significant (P <0.05); the control group, the total effective rate was 68.97% in children with treatment was 93.10% of the total treatment Effective, the difference was significant (P <0.05). Conclusion Montelukast combined with budesonide in children with cough variant asthma obvious effect, can effectively improve the clinical symptoms and lung function, improve the therapeutic effect, it is worth promoting.