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灭囊灵是中药复方制剂,临床主要用于治疗脑囊虫病或脑囊虫病继发引起的癫痫发作、颅内压增高等症状或病理改变。为研究灭囊灵的抗惊厥作用,本实验观察了灭囊灵及其成分全蝎、矾石、水蛭对小鼠的电惊厥及回苏灵、硝酸士的宁引起的小鼠的化学惊厥的影响。材料与方法1 动物昆明种小鼠,体重18～22g,中山医科大学动物中心提供。2 药物与试剂灭囊灵由全蝎、矾石、水蛭构成(按1:1:1投料),灭囊灵及其单味药均为粉剂,本院中药制剂室提供,实验前用5％淀粉配成混悬液;回苏灵(二甲弗林)注射液,上海第一制药厂生产,批号:940301;硝酸士的宁注射液,上海禾丰制药有
Extinguishing capsule is a traditional Chinese medicine compound preparation. It is mainly used for the treatment of cerebral cysticercosis or cerebral cysticercosis secondary to seizures, increased intracranial pressure, or pathological changes. In order to study the anticonvulsant effect of zetongling, this experiment observed the chemical convulsions of mice caused by eclenoxacin and its components holmium, vermiculite, leeches and mice induced by electroconvulsions in mice and cisplatin and strychnine nitrate. influences. Materials and Methods Animal Kunming mice weighing 18-22 g were provided by Animal Center of Sun Yat-Sen University of Medical Sciences. 2 Drugs and Reagents Excyleng is composed of total hydrazine, vermiculite, and bismuth (according to 1:1:1 dosage). Extinguishing capsule and its single herb are powders. It is provided in the Chinese medicine preparation room of the hospital and used 5% before the experiment. Starch dubbed suspension; Huisulin (Dimethylfolin) injection, manufactured by Shanghai No. 1 Pharmaceutical Factory, batch number: 940301; strychnine nitrate injection, Shanghai Fufeng Pharmaceutical Co., Ltd.