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目的研究血清D二聚体和超敏C反应蛋白(hs-CRP)在老年进展性脑梗死患者中的应用价值。方法 172例老年急性脑梗死患者分为进展组和非进展组,分别检测其血清D二聚体和hs-CRP水平并比较差异,并与50例非脑血管病患者进行比较。结果脑梗死组血清D二聚体和hs-CRP水平显著高于对照组(P=0.001);进展组患者血清D二聚体和hs-CRP水平显著高于非进展组(P=0.001)。结论 D二聚体和hs-CRP水平检测有助于老年进展性脑梗死患者的早期诊断和预后的评估。
Objective To investigate the value of serum D-dimer and hs-CRP in elderly patients with advanced cerebral infarction. Methods A total of 172 elderly patients with acute cerebral infarction were divided into progressive group and non-progressive group. The levels of serum D-dimer and hs-CRP were measured and compared with those of 50 non-cerebrovascular patients. Results The levels of serum D-dimer and hs-CRP in cerebral infarction group were significantly higher than those in control group (P = 0.001). The levels of serum D-dimer and hs-CRP in progression group were significantly higher than those in non-progression group (P = 0.001). Conclusion The detection of D-dimer and hs-CRP is helpful for the early diagnosis and prognosis evaluation of elderly patients with advanced cerebral infarction.