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流产是常见的妊娠并发症,其病因较为复杂,自身免疫因素被认为是导致流产的重要因素之一。在一些发生不明原因反复流产的妇女体内,常常会分离到一些自身抗体,其中以抗磷脂抗体(antiphospholipid antibody,APA)最为普遍。抗磷脂综合征(antiphospholipid syndrome,APS)是近十几年来临床上新发现的一种非器官特异性的自身免疫性疾病,其主要特征是与其体内的APA密切相关,其临床症状主要包括血栓形成、习惯性流产、血小板减少、溶血性贫血、肢端顽固性溃疡等。这些症状可单一出现,也可多个并存。本文主要讨
Abortion is a common pregnancy complication, the etiology is more complicated, autoimmune factors are considered as one of the important factors leading to abortion. In some women with unexplained recurrent miscarriage, some autoantibodies are often isolated, of which antiphospholipid antibody (APA) is the most common. Antiphospholipid syndrome (APS) is a non-organ-specific autoimmune disease newly discovered clinically in recent decades. Its main feature is closely related to its APA in vivo, and its clinical symptoms mainly include thrombosis , Habitual abortion, thrombocytopenia, hemolytic anemia, stubborn ulcers and other extremities. These symptoms can appear alone, but also co-exist. This article mainly discuss