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为探讨化脓性、结核性、病毒性脑膜炎患者脑脊液（ＣＳＦ）中前白蛋白（ＰＡ）、Ｎ乙酰βＤ氨基葡萄糖苷酶（ＮＡＧ）、肌酸激酶Ｂ亚基（ＣＫＢ亚基）、谷草转氨酶（ＡＳＴ）与乳酸脱氢酶（ＬＤ）５种成分的变化规律，用常规方法测定以上５种指标的含量。结果：３组患者ＣＳＦ中ＰＡ明显低于对照组；ＮＡＧ、ＣＫＢ亚基与ＬＤ活性显著增高，以化脓性脑膜炎改变最显著；除ＬＤ、ＡＳＴ外其他指标在结核性脑膜炎与病毒性脑膜炎间无明显差异；ＡＳＴ活性高于对照组，且化脓性脑膜炎＞病毒性脑膜炎＞结核性脑膜炎。结论：测定ＣＳＦ中５种成分对鉴别３种脑膜炎有一定临床价值；每组患者ＣＳＦ中５种成分含量的改变无相关关系，可能与发病机制、疾病部位与严重程度及此物质在脑内分布特点、异常代谢不同有关。
In order to investigate the relationship between the serum levels of prealbumin (PA), NacetylβDglucosaminidase (NAG), creatine kinase B subunit (CKC) in purulent, tuberculous and viral meningitis patients, B subunit), aspartate aminotransferase (AST) and lactate dehydrogenase (LD) were measured. The contents of these five indexes were determined by routine methods. Results: PA in 3 groups of patients was significantly lower than that in control group; NAG, CKB subunit and LD activity were significantly increased, the most significant changes in purulent meningitis; other indicators in addition to LD, AST in tuberculous meningitis and virus No significant difference between meningitis; AST activity was higher than the control group, and purulent meningitis> viral meningitis> tuberculous meningitis. Conclusion: The determination of five components of CSF has certain clinical value in the identification of three kinds of meningitis. There is no correlation between the content of five components in the CSF of each group, which may be related to the pathogenesis, the location and severity of the disease, Distribution characteristics, abnormal metabolism related to different.