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目的探讨检测麻疹IgM抗体对分析麻疹流行病学特征的意义。方法对江苏省如东县2006—2009年141例麻疹疑似病例采集血清标本,应用酶联免疫吸附试验(ELISA)捕获法检测麻疹IgM抗体,对检测结果应用χ2检验进行统计学处理。结果 141例麻疹疑似病例血清标本,麻疹IgM抗体阳性109例,阳性率77.30%。11～20岁年龄组阳性率最高,达90.32%;31～40岁组次之,为84.78%。在病例的职业构成中农民占45.68%。在病例的免疫史分布中,无免疫史、免疫史不详者合计达69.14%。结论该县麻疹发病有向大年龄组发展的趋势,农民为重要的发病人群。加强麻疹疫苗接种管理尤其是农村的管理、针对成人的后续强化免疫和应急接种对控制疫情的传播具有重要意义。
Objective To investigate the significance of measles IgM antibody in the analysis of epidemiological characteristics of measles. Methods Serum samples were collected from 141 suspected cases of measles in Rudong County of Jiangsu Province during 2006-2009. Measles IgM antibodies were detected by enzyme-linked immunosorbent assay (ELISA) capture method. The test results were analyzed by χ2 test. Results 141 cases of measles suspected cases of serum samples, measles IgM antibody positive 109 cases, the positive rate of 77.30%. The highest positive rate was found in 11 ~ 20 years old group, reaching 90.32%; followed by 31 ~ 40 years old group was 84.78%. In the occupational structure of the cases, peasants accounted for 45.68%. In the distribution of the case history of immunization, no history of immunization, unknown history of immunization totaled 69.14%. Conclusion The incidence of measles in the county tends to develop in the older age group, and the peasants are an important incidence group. Strengthening the management of measles vaccination, especially in rural areas, and the follow-up intensive immunization and emergency vaccination against adults are of great significance in controlling the spread of the epidemic.