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外阴上皮非瘤样病变是一组女性外阴和粘膜组织发生色素改变和变性的常见病变,是以外阴瘙痒、皮肤粘膜色素减退为特征的慢性疾病。包括鳞状上皮增生(SHV)、硬化性苔藓(LSV)和外阴硬化性苔癣合并鳞状上皮增生(LSCSH)三种病理类型。外阴鳞状上皮增生是以外阴瘙痒和鳞状上皮增生为主;硬化性苔藓则以外阴及肛门皮肤萎缩变薄变白,弹性减退致阴道口狭窄,性交困难为特征。组织学变化均发生在真皮层,以毛细血管痉挛闭塞致局部微循环或真皮浅层微小血管减少血氧供不足,使表皮发生不同程度病变;硬化性苔癣合并鳞状上皮增生为鳞状上皮增生,硬化性苔癣两种病变同时存在,程度不一。它是一种病程长,病情顽固的妇科疾患,严重影响患者生活质量和身心健康。因其病因未明,无特效治疗方法。2007年1月-2015年1月对我院妇科门诊诊治62例外阴上皮非瘤样病变应用臭氧水冲洗外阴、阴道臭氧雾化外阴、阴道治疗,获得满意效果,现报道如下:
Vulvar epithelial non-tumor-like lesions are a group of female vulva and mucosal tissue pigment changes and degeneration of the common lesions, genital itching, skin mucosal hypopigmentation is characterized by chronic diseases. Including three pathological types of squamous epithelial hyperplasia (SHV), sclerosing lichen (LSV) and vulvar lichen sclerosis with squamous cell hyperplasia (LSCSH). Vulvar squamous hyperplasia is the vulva pruritus and squamous epithelial hyperplasia; sclerosing moss while the genital and anal skin atrophy thinning white, elastic reduction caused vaginal stenosis, dyspareunia is characterized. Histological changes occurred in the dermis, with capillary spasm occlusion caused by local microcirculation or shallow superficial dermis to reduce blood oxygen deficiency, the epidermis of varying degrees of lesions; scleroses lichen sclerosis complicated with squamous epithelium Hyperplasia, lichen sclerosis two lesions exist at the same time, varying degrees. It is a long duration, stubborn gynecological conditions, seriously affecting the quality of life of patients and physical and mental health. Because of its etiology is unknown, no specific treatment. January 2007-January 2015 in our hospital outpatient diagnosis and treatment of 62 cases of vulvar epithelial non-tumor-like lesions using ozone water to wash the vulva, vaginal ozone atomization of the vulva, vaginal treatment, to obtain satisfactory results are reported below: