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(目的)观察抗肿瘤新药康莱特(KLT)乳加顺铂(DDP)联合治疗恶性胸腔积液的疗效。(方法)治疗恶性胸腔积液30例。治疗组15例KLT乳200ml+DDP40mg胸腔内注入;对照组15例单用顺铂100mp胸腔内注入。(结果)治疗组CR为66.7%(10/15),无毒副作用出现;对照组CR为26.7%(4/15),出现消化道反应3例,肾毒性反应1例。(结论)以KLT乳加DDP联合腔内化疗治疗恶性胸腔积液有效率高,毒副反应轻,是一值得推广的疗法。
(Objective) To observe the efficacy of Kang Laite (KLT) plus cisplatin (DDP) in the treatment of malignant pleural effusion. (Method) 30 cases of malignant pleural effusion were treated. In the treatment group, 15 cases of KLT milk 200ml+DDP 40mg were injected into the chest; in the control group, 15 cases were injected with cisplatin 100mp intrapleurally. (Results) CR in the treatment group was 66.7% (10/15), with no toxic or side effects; CR in the control group was 26.7% (4/15), 3 cases of digestive tract reaction and 1 case of nephrotoxicity. (Conclusion) The use of KLT plus DDP combined with intraluminal chemotherapy for the treatment of malignant pleural effusions is effective and has a mild toxicity. It is worthy of promotion.