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NO是一种参与血管扩张、神经传导、免疫性炎症等的信使分子。由iNOS合成的NO参与了抗微生物感染、杀伤肿瘤细胞和抗致死性内毒素血症等作用。由巨噬细胞产生的NO还可抑制ConA刺激的脾细胞增殖和绵羊红细胞抗体应答。 研究发现,从人参中分离出的多糖成分具有杀伤肿瘤细胞和诱导巨噬细胞产生细胞因子的活性。酸性多糖(RGAP)分离自人参不溶于乙醇而溶于水的部分,化学成分检测发现其含有56.9％酸性糖和
NO is a messenger involved in vasodilation, nerve conduction, and immune inflammation. Nitric oxide synthesized by iNOS participates in anti-microbial infection, killing tumor cells and preventing fatal endotoxemia. NO produced by macrophages also inhibits ConA-stimulated splenocyte proliferation and sheep erythrocyte antibody responses. Studies have found that the polysaccharide component isolated from ginseng has the activity of killing tumor cells and inducing cytokine production by macrophages. Acidic polysaccharide (RGAP) was isolated from ginseng which is insoluble in ethanol and soluble in water. Chemical composition tests revealed that it contained 56.9% of acidic sugars and