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目的探讨甲状腺功能亢进症(甲亢)并肝脏损害的临床特点及治疗措施。方法回顾性分析1996年7月至2009年7月1268例甲亢患者的临床资料。结果 1268例甲亢中382例发生肝脏损害,发生率30.1%。甲亢病程越长,随着血清FT3、FT4水平的增高,肝损害更趋明显。肝脏损害主要表现为消化道症状,但半数以上患者无临床症状,食欲大多数正常或亢进。结论甲亢并肝脏损害与患者的年龄、病程和血清FT3、FT4水平有关。对于甲亢患者应常规检查肝功能了解有无肝脏损害。甲亢性肝损害如诊断及时,治疗积极,预后良好。
Objective To investigate the clinical features and treatment of hyperthyroidism (Hyperthyroidism) and liver damage. Methods The clinical data of 1268 hyperthyroid patients from July 1996 to July 2009 were analyzed retrospectively. Results In 1268 cases of hyperthyroidism, 382 cases of liver damage occurred, the incidence of 30.1%. The longer course of hyperthyroidism, with the increase of serum FT3, FT4 levels, liver damage is more obvious. Liver damage is mainly manifested as gastrointestinal symptoms, but more than half of patients without clinical symptoms, most of the appetite normal or hyperthyroidism. Conclusions Hyperthyroidism and liver damage are related to the patient’s age, course of disease and serum levels of FT3 and FT4. Hyperthyroidism patients should routinely check the liver function to understand whether there is liver damage. Hyperthyroidism, such as timely diagnosis of liver damage, positive treatment, a good prognosis.