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目的采用不同浓度盐水雾化吸入辅助治疗婴幼儿毛细支气管炎的临床疗效。方法婴幼儿毛细支气管炎患儿60例,按照数字随机法分为三组,每组20例,第1组为0.9%生理盐水+地塞米松雾化吸入辅助治疗,为对照组;第2组为3%高渗盐水+地塞米松雾化吸入辅助治疗,为观察组1;第3组为5%高渗盐水+地塞米松雾化吸入辅助治疗,为观察组2。结果对照组总有效率80%,观察1组总有效率95%,观察2组总有效率90%,观察组1总有效率明显比观察组2和对照组高,差异有统计学意义(P<0.05)。观察组1咳嗽和肺部哮鸣音消失时间及住院时间均短于观察组2和对照组,差异有统计学意义(P<0.05)。结论 3%浓度盐水雾化吸入辅助治疗婴幼儿毛细支气管炎是一种安全高效的理想治疗方法。
Objective To study the clinical effects of inhalation with different concentrations of saline in the treatment of infantile bronchiolitis. Methods Sixty infants with bronchiolitis were divided into three groups (n = 20 in each group). The first group received 0.9% saline plus dexamethasone nebulization as adjuvant therapy. The second group 3% hypertonic saline + dexamethasone nebulized inhalation adjuvant therapy for the observation group 1; the third group was 5% hypertonic saline + dexamethasone nebulized inhalation adjuvant treatment for the observation group 2. Results The total effective rate was 80% in the control group. The total effective rate in the observation group 1 was 95%. The total effective rate in the observation group 2 was 90%. The total effective rate in the observation group 1 was significantly higher than that in the observation group 2 and the control group (P <0.05). Observation group 1 cough and lung wheeze disappear time and hospital stay were shorter than the observation group 2 and the control group, the difference was statistically significant (P <0.05). Conclusions The 3% saline inhalation is an ideal and safe treatment for infantile bronchiolitis.