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目的观察并评价阿奇霉素治疗小儿支原体肺炎的有效性和安全性。方法 69例支原体肺炎的患儿随机分为治疗组和对照组,治疗组35例予阿奇霉素静脉滴注、对照组34例予红霉素静脉滴注,比较两组治疗的疗效与不良反应。结果治疗组总有效率为94.29%,对照组总有效率为91.18%,两组比较差异无统计学意义(P>0.05);治疗组较对照组不良反应少,能明显降低患者胃肠道反应(P<0.01)和局部静脉疼痛(P<0.01)。结论阿奇霉素治疗小儿支原体肺炎的疗效好,不良反应少,安全性较高,值得临床广泛运用。
Objective To observe and evaluate the efficacy and safety of azithromycin in the treatment of mycoplasma pneumonia in children. Methods 69 cases of mycoplasma pneumonia were randomly divided into treatment group and control group. 35 cases were treated with azithromycin in the treatment group and 34 cases were given erythromycin intravenously in the control group. The curative effects and adverse reactions of the two groups were compared. Results The total effective rate was 94.29% in the treatment group and 91.18% in the control group, with no significant difference between the two groups (P> 0.05). The treatment group had less side effects than the control group, which could significantly reduce the gastrointestinal reaction (P <0.01) and local venous pain (P <0.01). Conclusion Azithromycin treatment of children with mycoplasma pneumonia is effective, less adverse reactions, higher safety, it is widely used in clinical.