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1998年9月～2002年9月,我院因前列腺疾病住院行血清前列腺特异抗原(PSA)检查的患者共425例,其中经活检或手术病理确诊为前列腺癌(PCa)者48例,随机抽取经手术确诊的50例前列腺增生(BPH)患者为对照组,分析比较两组患者PSA检测结果,以探讨PSA对PCa的诊断价值。 资料与方法:PCa组48例,年龄57～88岁,平均71.8岁。BPH组50例,年龄62～86岁,平均69.3岁。两组患者均有膀胱出口梗阻症状。PCa组伴有血尿7例,远处转移症状11例,尿潴留4例;BPH组伴有血尿12例,尿潴留9例。PCa组临床分期:T_1期6例,T_2期18例,T_3期13例,T_4期11例。 方法:采血前1周内禁行直肠指检、前列腺穿刺、尿道内器械检查。空腹抽静脉血2ml,分离血清,备检。采用化学发光免疫法检测,ACS:180SE全自动化学发光免疫分析仪及配
From September 1998 to September 2002, a total of 425 patients with PSA in our hospital were enrolled, of whom 48 were diagnosed as prostate cancer (PCa) by biopsy or surgical pathology and were randomly selected 50 cases of benign prostatic hyperplasia (BPH) confirmed by operation were the control group. The PSA test results of two groups were compared to explore the diagnostic value of PSA on PCa. Materials and Methods: PCa group of 48 patients, aged 57 to 88 years, mean 71.8 years. BPH group 50 cases, aged 62 to 86 years, mean 69.3 years. Both groups had bladder outlet obstruction symptoms. PCa group had hematuria in 7 cases, distant metastasis in 11 cases and urinary retention in 4 cases; BPH group had hematuria in 12 cases and urinary retention in 9 cases. The clinical stage of PCa group was T_1 6 cases, T_2 18 cases, T_3 13 cases and T_4 11 cases. Methods: Proximal rectal examination, prostatic puncture and intraurethral instrumentation were performed within 1 week before blood sampling. Fasting venous blood 2ml, serum was separated for the test. Using chemiluminescence immunoassay, ACS: 180SE automatic chemiluminescence immunoassay analyzer and