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目的:分析胃炎胃溃疡患者治疗中不合理用药的相关因素,为此类疾病临床合理用药提供参考。方法:选取2014年1月—2015年12月间收治的胃炎胃溃疡患者150例,按收治时间的不同将其分为A组(2014年1月—2014年12月)75例和B组(2015年1月—2015年12月)75例;分析两组患者不合理用药的相关因素以及治疗后的总有效率、不良反应的发生率和复发率。结果:75例患者不合理用药类型有配伍不当、剂量过多或过少、重复用药、用药选择不当、无指征用药,其中配伍不当49例占65.33%,用药选择不当10例占13.33%,重复用药7例占9.33%;治疗的总有效率B组为97.33%高于A组为77.33%(P<0.05);其不良反应的发生率(9.33%)和复发率(10.67%)均低于A组(21.33%和28.00%)(P<0.05)。结论:胃炎胃溃疡患者的不合理用药主要体现在配伍不当、用药选择不当、重复用药等方面,从而导致临床治疗的有效率下降,而不良反应的发生率、复发率上升,临床上应重视此类疾病的合理用药,正确掌握胃炎胃溃疡患者的临床病症,采用不同种类的胃炎、胃溃疡疾病的治疗药物。
Objective: To analyze the related factors of unreasonable medication in the treatment of patients with gastritis and gastric ulcer and to provide a reference for the clinical reasonable medication of such diseases. Methods: One hundred and fifty patients with gastritis and gastric ulcer admitted from January 2014 to December 2015 were selected and divided into group A (January 2014-December 2014) and group B January 2015-December 2015). The related factors of irrational drug use and the total effective rate, incidence of adverse reactions and relapse rate after treatment were analyzed. Results: The unreasonable types of medication in 75 patients were improper compatibility, overdosage or too little dosage, repeated medication, improper medication selection and no indications. Among them, 49 patients (65.33%) with improper compatibility, 10 (13.33%) patients with inappropriate medication, The total effective rate in treatment group B was 97.33%, which was significantly higher than that in group A (77.33%) (P <0.05). The incidence of adverse reactions (9.33%) and recurrence rate (10.67%) were both low In group A (21.33% and 28.00%) (P <0.05). Conclusion: Irrational drug use in patients with gastritis and gastric ulcer mainly manifests in improper compatibility, improper medication selection and repeated medication, which leads to the decrease of the effective rate of clinical treatment, but the incidence of adverse reactions and recurrence rate increase, which should be valued clinically Rational use of drugs, the correct understanding of the clinical symptoms of gastritis and gastric ulcer patients, the use of different types of gastritis, gastric ulcer disease treatment drugs.