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近十余年来,由于联合化疗和合理用药,白血病治疗后“完全缓解”(complete remission)的病例越来越多。但其缓解后复发率也高。故目前在白血病的诊治中关键问题是:如何巩固缓解期疗效、防止其复发;白血病缓解期病理改变如何;复发的瘤细胞来自何处;白血病化疗后缓解期多长可作为真正治愈的标准等。我们通过白血病尸解材料的观察和分析,从缓解病例的病理组织学的改变,探讨白血病复发的原因,为临床更有效的治疗提供线索。
In the past decade or so, there have been more and more cases of “complete remission” after leukemia treatment due to combination chemotherapy and rational drug use. However, the recurrence rate after remission is also high. Therefore, the current diagnosis and treatment of leukemia in the key issues are: how to consolidate the efficacy of remission, to prevent recurrence; leukemia remission pathological changes; recurrence of tumor cells from where; how long after remission of leukemia can be used as a real cure standard . Through the observation and analysis of leukemic autopsy materials, we explored the reasons for the relapse of leukemia from alleviating the histopathological changes and providing clues for more effective clinical treatment.