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目的探讨微血管性心绞痛患者是否存在胰岛素抵抗现象。方法对39例微血管性心绞痛患者(MA组)和32例正常人(NS组)进行对比,观察空腹血糖(FBG)、空腹胰岛素水平(Fins)和胰岛素敏感性指数(ISI)的变化。结果MA组与NS组空腹血糖无明显差异但MA组空腹胰岛素水平明显升高(P<0.05)、胰岛素敏感性指数明显降低(P<0.01)。结论微血管性心绞痛患者存在高胰岛素血症及胰岛素抵抗。
Objective To investigate the existence of insulin resistance in patients with microvascular angina. Methods The changes of fasting blood glucose (FBG), fasting insulin (Fins) and insulin sensitivity index (ISI) in 39 patients with microvascular angina (MA group) and 32 normal subjects (NS group) were compared. Results There was no significant difference in fasting blood glucose between MA group and NS group, but the fasting insulin level in MA group was significantly increased (P <0.05) and the insulin sensitivity index was significantly decreased (P <0.01). Conclusions There is hyperinsulinemia and insulin resistance in patients with microvascular angina.