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透明细胞乳头状肾细胞癌逐渐被视为一种具有独特的形态学、免疫表型和细胞遗传学特点的肿瘤,其组织病理学特征常常类似透明细胞性肾细胞癌,但是未见转移的报道。因此,该肿瘤可能是一种非侵袭性肿瘤,认识到这一点具有非常重要的临床意义。作者采用免疫组织化学、荧光原位杂交或染色体核型分析技术,对22例患者(年龄33~82岁)具有交界性形态学特点的透明细胞乳头状肾细胞癌进行分析。结果发现,22例肿瘤中,与透明细胞乳头状肾细胞相似的形态学表现所占比例从
Transparent cell papillary renal cell carcinoma is gradually being considered as a tumor with unique morphological, immunophenotypic and cytogenetic characteristics, and its histopathological features are often similar to clear cell renal cell carcinoma, but no metastasis has been reported . Therefore, the tumor may be a non-invasive tumor, recognizing this point has a very important clinical significance. The authors used immunohistochemistry, fluorescence in situ hybridization or chromosomal karyotyping techniques to analyze the borderline morphological features of 22 patients (aged 33-82 years) with clear cell papillary renal cell carcinoma. The results showed that 22 cases of tumors, and clear cell papillary renal cells similar to the proportion of morphological changes from