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过去,宫颈因素的冶疗妊娠率低于30%。小剂量雌激素可能刺激改善宫颈粘液,大剂量雌激素则更有效。但小剂量雌激素干扰排卵,大剂量雌激素在大多数病例中抑制垂体促性腺激素。于是设计了大剂量雌激素刺激粘液腺和外源性促性腺激素(人绝经期促性腺激素,hMG)直接刺激卵巢滤泡的方法,本文报导34例宫颈因素疾病用其他常规方法无效而用此法治疗的结果。34例仅为宫颈因素的不孕患者(配偶精液常规正常;子宫输卵管造影或腹腔镜显示输卵管通畅;排卵功能好,月经前一周血清孕酮大于10ng/ml),宫颈粘液质量差(通过拉丝度、细胞构成和量来判
In the past, cervical pregnancy rate of less than 30% of the treatment. Low doses of estrogen may stimulate the improvement of cervical mucus, high-dose estrogen is more effective. However, small doses of estrogen interfere with ovulation, and high doses of estrogen inhibit pituitary gonadotropin in most cases. So the design of large doses of estrogen stimulation of mucinous glands and exogenous gonadotropin (human menopausal gonadotropin, hMG) directly stimulate the ovarian follicles, the paper reported 34 cases of cervical disease with other conventional methods ineffective and use this The result of the treatment of law. 34 cases of infertility only cervical factors (normal spouses normal spleen or tubal tubal tubal tubal unobstructed; ovulation is good, a week before menstruation serum progesterone greater than 10ng / ml), poor quality cervical mucus (by drawing degrees , Cell composition and quantity to sentence