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目的对疏血通注射液与低分子肝素钙联合应用治疗急性脑梗死的疗效进行临床观察。方法采用随机对照方法,将60例急性脑梗死患者分成2组,每组30例。治疗组用疏血通注射液6ml,每日一次静点,共14天,低分子肝素钙0.4ml,每12小时腹部皮下注射1次,共用7天;对照组用参芎葡萄注射液200ml,奥扎格雷钠80mg加入液体中静脉滴注,1日1次,共14天。分别观察2组治疗前后临床疗效及血液学改变。结果经治疗,治疗组基本痊愈率40.0%,显效率43.3%;基本痊愈率及显效率均优于对照组(P<0.05)。治疗中未出现不良反应。结论疏血通注射液与低分子肝素钙联合应用治疗急性脑梗死,在改善临床症状及血液学指标方面均明显优于对照组。
Objective To observe the curative effect of Shuxuetong injection combined with low molecular weight heparin on acute cerebral infarction. Methods A randomized controlled trial of 60 patients with acute cerebral infarction was divided into two groups (n = 30 in each group). Treatment group with Shuxuetong injection 6ml once a day for a total of 14 days, low molecular weight heparin 0.4ml, abdominal subcutaneous injection once every 12 hours for 7 days; the control group with Shenxiong grape injection 200ml, Ozagrel sodium 80mg added to the liquid intravenous infusion, 1 on the 1st, a total of 14 days. Two groups were observed before and after treatment of clinical efficacy and hematological changes. Results After treatment, the cure rate in the treatment group was 40.0% and the effective rate was 43.3%. The basic cure rate and effective rate were both better than those in the control group (P <0.05). No adverse reactions during treatment. Conclusion Shuxuetong injection combined with low molecular weight heparin in the treatment of acute cerebral infarction were significantly better than the control group in improving clinical symptoms and hematological indexes.