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HCV的母婴传播虽已有报告,但传播程度尚不清楚。作者在前瞻性和回顾性研究中,通过分析母婴血液中的HCV RNA,以评价HCV的母婴传播率。 本研究包括第1、2项前瞻性研究和第3项回顾性研究。研究1(1990年5月~1992年12月):用第Ⅱ代酶免疫试验(EIA-Ⅱ)检测7 698例产妇的抗-HCV,对其中53例阳性母亲所生的54例婴儿随访至少6个月,并同时检测HCV RNA和抗-HCV。
Although the mother-to-child transmission of HCV has been reported, the extent of its spread is not clear. In a prospective and retrospective study, the authors assessed the maternal-to-infant transmission of HCV by analyzing HCV RNA in maternal and infant blood. This study included the first and second prospective studies and the third retrospective study. Study 1 (May 1990-December 1992): Anti-HCV was detected in 7 698 mothers using the enzyme-II assay (EIA-II), followed by at least 54 of the 53 mothers 6 months, and simultaneous detection of HCV RNA and anti-HCV.